Many countries have started vaccination programs against the Coronavirus, as the rapid development of vaccines makes great promises to stop the spread of the pandemic, and despite efforts to spread vaccines in many countries, challenges facing the supply chain have raised questions about whether giving a single dose instead of a dose Double might be enough for some individuals or not.
Researchers at Cedars-Sinai Medical Center in the United States evaluated the antibody response to Corona after the first and second doses of the ribonucleic acid (mRNA) vaccine, the Pfizer-BioNTech vaccine, which is administered in a large variety of healthcare workers.
The researchers found that people who were previously infected with Corona developed a level of the induced antibody response, even after receiving only one dose of the vaccine, this immune response can be compared to the stimulated response that appears after vaccination with two doses given to uninfected individuals.
According to the report of the "medicalnewstoday" website, the team noted the history of infection with Corona, and the timing was linked to the date of the first dose that was received, and then compared the levels of antibodies and symptom responses between those who had a previous diagnosis of Corona or not.
Vaccine recipients provided at least one blood sample for antibody testing, and among the recipients, 980 primary samples were provided, 525 samples were provided after the first dose, as well as 238 samples after the second dose.
The team found that, looking at the total sample, the percentage of antibody levels were higher in people who had recovered from Corona, compared to individuals who did not become infected after taking a single dose.
Moreover, the results of the study showed that people who recovered from Corona developed a level of the induced antibody response after only one dose of the vaccine, and this is similar to the response observed after the two doses given to people who were never infected.
With the challenges of supplying the vaccine and countries aiming to vaccinate most of their population, a single dose could provide protection for those infected, however, the researchers reiterated that more studies are needed to validate their findings.
The launch of the COVID-19 vaccine
Many countries have already started giving vaccines to their own citizens, and most of these countries have prioritized health care workers and at-risk groups, including the elderly and those with comorbidities.

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